Among persons aged 1217 years, reactions after Pfizer-BioNTech booster vaccination were generally mild to moderate and transient; the frequency of local and systemic reactions reported to v-safe after a booster dose were equal to or slightly higher than after the second primary dose. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. MMWR Morb Mortal Wkly Rep 2022;71:13945. The efficacy of the BNT162b2 (Pfizer-BioNTech) vaccine against laboratory-confirmed COVID-19 exceeded 90% in clinical trials that included children and adolescents aged 5-11, 12-15, and 16-17 years (1-3).Among children aged 5-11 years, VE against laboratory-confirmed COVID-19-associated ED and UC encounters 14-67 days after dose 2 (the longest interval after dose 2 in this age . Fifth, genetic characterization of patients viruses was not available, and Delta and Omicron predominance periods were based on surveillance data. Pfizer-BioNTech vaccine-related data, which the FDA relied on to grant Emergency Use Authorisation, can now be reviewed. The Pfizer-BioNTech vaccine is the first mRNA-based vaccination that enhances immunity. Generalized boosted regression trees were used to estimate the propensity to be vaccinated based on sociodemographic characteristics, underlying medical conditions, and facility characteristics. or. LISTEN: Does vaccination protect you against Omicron variant? Most hospitalizations of adolescents aged 1215 years (613 [82.7%]) and 1617 years (476 [70.7%]) occurred during Delta predominance, whereas two thirds of hospitalizations among children aged 511 years (190 [66.7%]) occurred during Omicron predominance. It was considered a vital component of living endemically with COVID-19. The Pfizer-BioNTech vaccine is the first mRNA-based vaccination that enhances immunity. The average side effects after the first dose were 79% compared with 84% after the second dose. 2021, filed with the SEC on March 30, 2022, . Acute myocarditis was defined as presence of signs and symptoms (one or more new or worsening of the following: chest pain/pressure/discomfort, dyspnea/shortness of breath/pain with breathing, palpitations, or syncope; or two or more of the following in children aged 11 years: irritability, vomiting, poor feeding, tachypnea, or lethargy); and one or more new finding of elevated troponin, electrocardiogram findings consistent with myocarditis, abnormal cardiac function or wall motion on echocardiogram, cardiac magnetic resonance imaging findings consistent with myocarditis, or histopathologic findings consistent with myocarditis; and no other identifiable cause for these findings. A certain 55,000 page document was released with the Pfizer vaccine side effects. However, most encounters among children aged 511 years occurred during Omicron predominance, when VE significantly declined for adolescents aged 1217 years. In a multistate analysis of 39,217 ED and UC encounters with COVID-19like illness among nonimmunocompromised patients aged 517 years through January 29, 2022, estimates of Pfizer-BioNTech VE against COVID-19associated ED and UC encounters varied by time since vaccination and by predominant circulating SARS-CoV-2 variant. Contact our traffic hotline: (031) 570 9400. For adolescents aged 1617 years, the study period began when COVID-19 vaccines became available to all those aged 16 years at each study site. The data in these analyses come from 306 ED and UC clinics and 164 hospitals. This report provides findings from v-safe and VAERS data collected during the first 711 weeks of administration of homologous Pfizer-BioNTech booster doses to persons aged 1217 years, during which time approximately 2.8 million booster doses were administered. Apart from any fair dealing for the purpose of private study or research, no Resulting in various adverse effects that may emerge after vaccination. Olson SM, Newhams MM, Halasa NB, et al. When seen in an emergency room approximately 13 days after vaccination, she was jaundiced and had mild hepatomegaly were negative. 552a; 44 U.S.C. . PFIZER vaccine adverse events pertaining to the liver and kidney are extremely rare. Approximately 0.9% (32) of adolescents reportedly received medical care during the week after booster dose vaccination; most (15; 0.4%) care was received via a clinic appointment. Prof Tulio answers. CDC is not responsible for the content
See this image and copyright information in PMC. Meo SA, Bukhari IA, Akram J, Meo AS, Klonoff DC. COVID-19 vaccine side effects commonly include arm soreness, headaches, fatigue, or light flu-like symptoms for a few days after the shotif any at all. Click here to sign in with MMWR Morb Mortal Wkly Rep 2008;57:45760. "We are encouraged by the outcome of today's meeting, as it is a testament to the strength of our science and dedication to bringing this important vaccine candidate to the market.". Would you like email updates of new search results? COVID-19 vaccine safety in adolescents aged 1217 yearsUnited States, December 14, 2020July 16, 2021. VE against COVID-19associated ED and UC encounters was substantially lower during the Omicron predominant period than the B.1.617.2 (Delta) predominant period among adolescents aged 1217 years, with no significant protection 150 days after dose 2 during Omicron predominance. Most VAERS reports were for nonserious events (837; 91.6%); the most commonly reported nonserious events included product storage error (123; 14.7%), dizziness (100; 12.0%), and syncope (87; 10.4%) (Table 2). We hope that our results will reassure the public that the benefits of vaccination far exceed the dangers. The FDA turned over thousands of documents related to its review of Pfizer-BioNTech's COVID-19 vaccine last week, marking the first of several releases mandated by a court in Texas earlier this year. considered spontaneously reported cases of suspected side effects, i.e. However, in adolescents aged 1617 years, VE during the Omicron predominant period increased to 81% 7 days after a third booster dose. https://www.meddra.org/how-to-use/basics/hierarchyexternal icon. They "may not have any causal relationship" to each. Burden of RSV Vaccination was defined as having received the listed number of doses of an mRNA-based COVID-19 Pfizer-BioNTech vaccine 14 days (for 2 doses) or 7 days (for 3 doses) before the medical event index date, which was the date of respiratory specimen collection associated with the most recent positive or negative SARS-CoV-2 test result before medical event or the admission date if testing only occurred after the admission. YDM: About 18 percent of the vaccine accumulates in the liver just 30 minutes after the vaccine is injected in mice as reported by Pfizer in EMA assessment report, and therefore we chose to study . An official website of the United States government. Pfizer-BioNTech COVID-19 Vaccine is a monovalent COVID-19 vaccine that is authorized for emergency use to prevent COVID-19 as: The first two doses of the three-dose primary series for children 6 . The phase IV clinical study analyses which people get Pfizer BioNTech Covid vaccine and have kidney stones. Phase 3 study (NCT04382326), which support the FDA application. Overall, 2-dose VE against COVID-19associated hospitalization was 73%94%. Among children aged 511 years, VE against laboratory-confirmed COVID-19associated ED and UC encounters 1467 days after dose 2 (the longest interval after dose 2 in this age group) was 46%. More information: Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. endorsement of these organizations or their programs by CDC or the U.S.
2020;382:727733. https://covid.cdc.gov/covid-data-tracker/#vaccination-demographic. Accessibility Pre-Delta refers to the period before Delta predominance. medical events that have been observed after vacci nation, but which are not necessarily related to or caused by the vaccine. Views equals page views plus PDF downloads. The FDA licensed the Pfizer vaccine on Aug. 23, 2021, just 108 days after Pfizer started producing the records to the agency. Among children aged 511 years, estimated VE of 2 vaccine doses received 1467 days earlier against COVID-19associated hospitalization was 74%, with wide confidence intervals that included zero (95% CI = 35% to 95%) (Table 2). Saving Lives, Protecting People, https://covid.cdc.gov/covid-data-tracker/#vaccination-demographic, https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm?fr, https://www.meddra.org/how-to-use/basics/hierarchy, https://www.fda.gov/media/150386/download, https://doi.org/10.1016/j.vaccine.2015.07.035, https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-09-22/02-COVID-Gruber-508.pdf, https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vaccines-us.html, Centers for Disease Control and Prevention, U.S. Department of Health & Human Services, Unable to perform normal daily activities, Inappropriate schedule of product administration, Insufficient data to make a clinical impression, Exacerbation of existing genetic disorder. The report by the FDA indicates that the COVID-19 Pfizer vaccine has over 1 200 side effects, that were not disclosed to the public, until last week. Walter EB, Talaat KR, Sabharwal C, et al. ** For children aged 511 years and adolescents aged 1215 years, the study period began 5 weeks after the Pfizer-BioNTech vaccine was recommended for their age group. The dates when the Delta and Omicron variants became predominant (accounted for >50% of sequenced viruses) were determined for each study site based on state and national surveillance data. Patients were excluded if they 1) were vaccinated before the CDC recommendation date for their age group, 2) received a third dose before booster doses were recommended for their age group, 3) received a booster dose <5 months after dose 2, 4) received 1 or >3 doses of the vaccine, or 5) if <14 days had elapsed since receipt of dose 2 or <7 days since dose 3. Each VAERS report might be assigned more than one MedDRA PT, which can include normal diagnostic findings; thus, the events listed in the table might sum to more than the total number of reports. You can unsubscribe at any time. The same panel of advisors will weigh the potential approval of another respiratory syncytial virus (RSV) vaccine . Pre-Delta refers to the period before Delta predominance. The panel voted 7-4, with one abstention, to recommend approval of the vaccine based on its efficacy, NBC News reported. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Among adolescents, reports to v-safe and VAERS after receipt of a booster dose were generally similar to those previously described after a primary series dose, reinforcing that vaccination among this population is safe (4,5). Reports of serious adverse events receive follow-up by VAERS staff to obtain additional information, including medical records and, for reports of death, death certificates and autopsy reports, if available. Centers for Disease Control and Prevention. Differences by time since vaccination were not statistically significant. Users are referred to the electronic PDF version (https://www.cdc.gov/mmwr)
Registrants aged 15 years must be enrolled by a parent or guardian. The vast majority of side effects from Pfizer and Moderna Covid vaccines are mild and subside within a day or two, according to a CDC study in the Lancet Infectious Diseases medical journal,. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. The information was only released on 8 March, Tuesday, in a 38-page report. Study selection process using preferred. CDC twenty four seven. During that period, the FDA asserts it conducted an intense, robust, and thorough analysis of those documents to assure the public that the Pfizer vaccine was safe and effective. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/children-teens.html (Accessed January 11, 2022). *** Chronic nonrespiratory condition was defined as the presence of discharge code for heart failure, ischemic heart disease, hypertension, other heart disease, stroke, other cerebrovascular disease, diabetes type I or II, other diabetes, metabolic disease, clinical obesity, clinically underweight, renal disease, liver disease, blood disorder, immunosuppression, organ transplant, cancer, neurologic disorder, musculoskeletal disorder, Down Syndrome, congenital heart disease, neurologic conditions, muscular dystrophy, sickle cell disease, prematurity (<24 weeks), developmental delay, technology dependence, or chronic gastrointestinal disease/irritable bowel syndrome. The South African Health Products Regulatory Authority (Sahpra) says it is investigating the data released on the report by the US Food and Drug Administration (FDA). On January 3, 2022, authorization was expanded to include persons aged 1215 years, and for all persons aged 12 years, the interval between dose 2 and booster dose was shortened to 5 months (1). Association of COVID-19 vaccination with symptomatic SARS-CoV-2 infection by time since vaccination and Delta variant predominance. Percentage of registrants who reported a reaction or health impact at least once during days 07 after vaccination. In partnership with CDC, the VISION Network* examined 39,217 emergency department (ED) and urgent care (UC) encounters and 1,699 hospitalizations among persons aged 517 years with COVID-19like illness across 10 states during April 9, 2021January 29, 2022, to estimate VE using a case-control test-negative design. Prof Tulio explains. Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of
Chronic respiratory condition was defined as the presence of discharge code for asthma, sleep apnea, or other lung disease using ICD-9 and ICD-10 diagnosis codes. If approved, 20vPnC would have the potential to cover more of the clinically significant remaining burden of infant pneumococcal disease than any other available pneumococcal conjugate vaccine. 2023 Jan 5;23(1):5. doi: 10.1186/s12879-022-07974-3. Serious reports to VAERS were reviewed by CDC physicians to form a clinical impression. HHS Vulnerability Disclosure, Help * Homologous refers to a booster dose of the same product administered for the primary series. Sect. endorsement of these organizations or their programs by CDC or the U.S.
As of February 20, 2022, only BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine has been authorized for use in persons aged 1217 years in the United States (1). Receipt of 2 Pfizer-BioNTech vaccine doses in persons aged 1217 years provided a high level of protection (>90%) against COVID-19associated hospitalizations within 149 days of receipt of the second dose. -, Clinical characteristics of coronavirus disease 2019 in China. 2023 Kagiso Media Ltd. All rights reserved. DOI: http://dx.doi.org/10.15585/mmwr.mm7109e2external icon. National Library of Medicine A statistically significant difference in VE or distributions of vaccination or infection status was indicated by nonoverlapping 95% CIs or standardized mean or proportion differences 0.2. and transmitted securely. In a tight vote, U.S. Food and Drug Administration advisors on Tuesday recommended the approval of an RSV vaccine that could be used in Americans ages 60 and up. sharing sensitive information, make sure youre on a federal The .gov means its official. This systematic review was undertaken to assess the Pfizer-BioNTech vaccine side effects by reviewing the previous studies. For general feedback, use the public comments section below (please adhere to guidelines). Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Indicates the reference group used for SMD calculations for dichotomous variables. * VE was calculated as [1 odds ratio] x 100%, estimated using a test-negative design, adjusted for age, geographic region, calendar time (days since January 1, 2021), and local virus circulation (percentage of SARS-CoV-2positive results from testing within the counties surrounding the facility on the date of the encounter) and weighted for inverse propensity to be vaccinated or unvaccinated. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Department of Health and Human Services. 1Kaiser Permanente Vaccine Study Center, Kaiser Permanente Northern California Division of Research, Oakland, California; 2Division of Child and Adolescent Health, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York; 3Department of Population and Family Health, Columbia University Mailman School of Public Health, New York, New York; 4NewYork-Presbyterian Hospital, New York, New York; 5Westat, Rockville, Maryland; 6Baylor Scott & White Health, Temple, Texas; 7Texas A&M University College of Medicine, Temple, Texas; 8Childrens Minnesota, Minneapolis, Minnesota; 9Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon; 10Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado; 11Center for Biomedical Informatics, Regenstrief Institute, Indianapolis, Indiana; 12Indiana University School of Medicine, Indianapolis, Indiana; 13Division of Infectious Diseases and Clinical Epidemiology, Intermountain Healthcare, Salt Lake City, Utah; 14CDC COVID-19 Emergency Response Team; 15HealthPartners Institute, Minneapolis, Minnesota; 16Fairbanks School of Public Health, Indiana University, Indianapolis, Indiana; 17Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, New York;18Regenstrief Institute, Indianapolis, Indiana; 19Vanderbilt University Medical Center, Nashville, Tennessee. Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of
; C4591001 Clinical Trial Group. Anaphylactic shock or severe reactions are rare. Prof Tulio explains, "Because I have had COVID-19 I will not get it for three months after I've had it?" CDC twenty four seven. ** The Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for the Pfizer-BioNTech vaccine for persons aged 16 years on December 11, 2020 (https://www.fda.gov/news-events/press-announcements/fda-takes-key-action-fight-against-covid-19-issuing-emergency-use-authorization-first-covid-19external icon), and CDC recommended the Pfizer-BioNTech vaccine on December 12, 2020 (https://www.cdc.gov/media/releases/2020/s1213-covid-vaccine.html). All eligible children and adolescents should remain up to date with recommended COVID-19 vaccinations, including a booster dose for those aged 1217 years. Pfizer-BioNTech COVID-19 vaccine letter of authorization. VAERS is a U.S. national passive vaccine safety surveillance system managed by CDC and FDA that monitors adverse events after vaccination (2). This study was reviewed and approved by the institutional review boards at participating sites or under a reliance agreement with the Westat, Inc. institutional review board.. All dose 2 and booster dose comparisons were statistically significant, except any systemic reaction and needed medical care. This. All eligible children and adolescents should remain up to date with recommended COVID-19 vaccinations, including a booster dose for those aged 1217 years.. Pfizer's new RSV vaccine for older adults may trigger the potentially deadly Guillain-Barre syndrome, the Food and Drug Administration has warned.. N Engl J Med 2020;383:260315. Questions or messages regarding errors in formatting should be addressed to
Compared with the Delta predominant period, estimated 2-dose VE for adolescents aged 1215 and 1617 years declined significantly once Omicron became the predominant variant: among adolescents aged 1617 years, VE of 2 doses received 150 days earlier against COVID-19associated ED and UC encounters declined from 77% during Delta predominance to a null VE (3%) during Omicron predominance; however, effectiveness of a third dose received 7 days earlier against COVID-19associated ED and UC encounters during Omicron predominance was 81%. N Engl J Med 2021;385:21013. Atlanta, GA: US Department of Health and Human Services, CDC; 2021. Suggested citation for this article: Hause AM, Baggs J, Marquez P, et al. This is still a very small amount of people, as it's only 29% of the country's population. 2020;11:1620. Among children aged 511 years during the full study period, VE of 2 doses (1467 days earlier) against COVID-19associated ED or UC encounters was 46%, which was significantly lower than overall estimates for adolescents aged 1217 years. The Food and Drug Administration (FDA) amended the Emergency Use Authorization (EUA) for Pfizer-BioNTech vaccine on December 9, 2021, to authorize a homologous* booster dose for persons aged 1617 years 6 months after receipt of dose 2 (1). One code in any of the four categories was sufficient for inclusion. DOI: http://dx.doi.org/10.15585/mmwr.mm7109e3external icon. -, The management of coronavirus disease 2019 (COVID-19) Liu J, Liu S. J Med Virol. "In older adults, RSV can result in serious illness, hospitalization, or even death, so there is a significant need to protect this at-risk population," Annaliesa Anderson, senior vice president and chief scientific officer for vaccine research and development at Pfizer, said in a news release announcing the panel decision. The https:// ensures that you are connecting to the This site uses cookies to assist with navigation, analyse your use of our services, collect data for ads personalisation and provide content from third parties. Unable to load your collection due to an error, Unable to load your delegates due to an error. In addition, the age SMD calculation comparing negative SARS-CoV-2 test result and positive SARS-CoV-2 test result was generated by directly calculating the SMD for negative SARS-CoV-2 test result and positive SARS-CoV-2 test result. An absolute SMD 0.20 indicates a nonnegligible difference in variable distributions between medical events for vaccinated versus unvaccinated patients; single SMD calculated by averaging pairwise comparisons of each vaccinated category versus unvaccinated and separately for patients with SARS-CoV-2positive versus SARS-CoV-2negative test results. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Please enable it to take advantage of the complete set of features! -. Vaccination was defined as having received the listed number of doses of COVID-19 Pfizer-BioNTech vaccine 14 days (for 2 doses) or 7 days (for 3 doses) before the medical event index date, which was the date of respiratory specimen collection associated with the most recent positive or negative SARS-CoV-2 test result before medical event or the admission date if testing only occurred after the admission. Side effects of Pfizer/BioNTech (BNT162b2) COVID-19 vaccine reported by the Birzeit University community. All statistical analyses were conducted using R software (version 4.1.2; R Foundation). Hepatotoxicity is the medical term fordamage to the liver caused by a medicine, chemical, or herbal or dietary supplement. The U.S. Centers for Disease Control and Prevention would also need to recommend the single shot before it could become available to Americans. Effectiveness of COVID-19 Pfizer-BioNTech BNT162b2 mRNA Vaccination in Preventing COVID-19Associated Emergency Department and Urgent Care Encounters and Hospitalizations Among Nonimmunocompromised Children and Adolescents Aged 517 Years VISION Network, 10 States, April 2021January 2022. Among adolescent boys, the reporting rate for confirmed cases of myocarditis after Pfizer-BioNTech booster vaccination was 11.4 per 1 million booster doses administered. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Chronic respiratory condition was defined as the presence of discharge code for asthma, sleep apnea, or other lung disease using ICD-9 and ICD-10 diagnosis codes. Most reports of administration errors mentioned that no adverse event was associated with receipt of an incorrect dose. https://www.meddra.org/how-to-use/basics/hierarchyexternal icon. WATCH: Dr Gcina Mhlophe welcomed to ECR by East Coast Breakfast. Shimabukuro TT, Nguyen M, Martin D, DeStefano F. Safety monitoring in the Vaccine Adverse Event Reporting System (VAERS). Local reactions in persons aged 6-23 months, Pfizer BioNTech BNT162b2 COVID-19 vaccine and placebo a Mild: 0.5 to 2.0 cm; moderate: >2.0 to 7.0 cm; severe: >7.0 cm; Grade 4: necrosis (redness and swelling categories) or exfoliative dermatitis (redness category only) regarding Pfizer/BioNTech'sproposal for the clinical and post-authorization safety data package for the Biologics License Application (BLA) for ourinvestigational COVID-19 Vaccine (BNT162b2). AFP To date, there have been 17-million people vaccinated in South Africa. 2022 Aug 26;15:6821-6836. doi: 10.2147/IJGM.S376316. No other potential conflicts of interest were disclosed. Pfizer has also tested its RSV vaccine in pregnant women. MMWR Morb Mortal Wkly Rep 2021;70:10538. If you feel any of these symptoms in the days or weeks after the vaccine, you should see a healthcare professional, such as a GP, afterhours service or emergency department - there will be no charge for the consultation. You can unsubscribe at any time and we'll never share your details to third parties. 2022 Nov 25;10(12):2012. doi: 10.3390/vaccines10122012. We would have not known that the following are side effects of the Pfizer vaccine for that long. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. The Adverse Reactions of Pfizer BioNTech COVID-19 Vaccine Booster Dose are Mild and Similar to the Second Dose Responses: A Retrospective Cross-Sectional Study. Questions or messages regarding errors in formatting should be addressed to
Safety Monitoring of COVID-19 Vaccine Booster Doses Among Persons Aged 1217 Years United States, December 9, 2021February 20, 2022. Charles Licata, Isaac McCullum, Bicheng Zhang. *** Chronic nonrespiratory condition was defined as the presence of discharge code for heart failure, ischemic heart disease, hypertension, other heart disease, stroke, other cerebrovascular disease, diabetes type I or II, other diabetes, metabolic disease, clinical obesity, clinically underweight, renal disease, liver disease, blood disorder, immunosuppression, organ transplant, cancer, neurologic disorder, musculoskeletal disorder, Down Syndrome, congenital heart disease, neurologic conditions, muscular dystrophy, sickle cell disease, prematurity (<24 weeks), developmental delay, technology dependence, or chronic gastrointestinal disease/irritable bowel syndrome. This odds ratio was adjusted for age, geographic region, calendar time (days from January 1), and local virus circulation in the community and weighted for inverse propensity to be vaccinated or unvaccinated. N Engl J Med. However, vaccine effectiveness (VE) was lower during Omicron predominance and decreased with time since vaccination; a booster dose restored VE to 81% among adolescents aged 1617 years. Syncope after vaccinationUnited States, January 2005July 2007. 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Estimated date of Delta and Omicron predominance at contributing sites: California (Delta: June 23, 2021; Omicron: December 21, 2021); Colorado (Delta: June 3, 2021; Omicron: December 19, 2021); Indiana (Delta: June 23, 2021; Omicron: December 26, 2021); Minnesota and Wisconsin (Delta: June 28, 2021; Omicron: December 25, 2021); New York (Delta: June 30, 2021; Omicron: December 18, 2021); Oregon and Washington (Delta: June 30, 2021; Omicron: December 24, 2021); Texas (Delta: July 3, 2021; Omicron: December 16, 2021); Utah (Delta: June 1, 2021; Omicron December 24, 2021). Events pertaining to the liver caused by the vaccine adverse events pertaining to the period Delta... Help * Homologous refers to a booster dose of the BNT162b2 mRNA vaccine... Observed after vacci nation pfizer vaccine side effects released march 2022 but which are not necessarily related to or caused by the based... 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