No Excess Cancer Risk from Radioactive Iodine Treatment in Radioactive iodine therapy … Avoid sleeping in the same bed with a pregnant … Author information: (1)Department of Endocrinology, Singapore General Hospital, Singapore 2. In August I was diagnosed with Graves Disease- I had all the scans done along with radioactive iodine uptake which pointed to Graves disease.Right before Radioactive Iodine treatment was started They found a nodule and had it biopsied. Stay at least six feet away from other people, including members of the public, family members, and co-workers, for three to 11 days. We immediately moved forward to discussing treatment options, and the doctor was quite pushy in his recommendation of radioactive iodine. Properly treated hypothyroidism is seen as a much less serious problem than Graves. This study reports a new observation that there may be a negative impact of RAI treatment on long-term QoL measures in patients with Graves’ disease. SF-36 measures general health status, including physical, mental, and social function and well-being. ? Quality of Life Is Worse at 6-10 Years after Radioactive Iodine Treatment of Graves’ Disease as Compared with Antithyroid Drugs or Surgery Sun Y. Lee Sun Y. Lee Section of Endocrinology, Diabetes, and Nutrition; Department of Medicine, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts, U.S.A. Radioactive Iodine (RAI), I 131 is one of the treatments for Graves’ disease and thyroid cancer. i have graves disease. Graves’ disease is typically treated with anti-thyroid medication, radioactive iodine therapy, or surgery. Overall, patients with treated Graves’ disease had worse scores on thyroid-related QoL measures, as assessed by ThyPRO, than the general population. I've had a lot of success with eating a keto diet - I lost 30 lbs in 5 months last year and the doctor decreased my synthroid dosage. Patients were treated according to usual clinical practice. So what she really want any of the other 5 massage can increase your immune system. In this study, quality of life scores were worse in patients with Graves’ disease treated with radioactive iodine therapy compared to antithyroid drugs or surgery at 6-10 years after treatment. The authors concluded that, for every 1,000 patients treated with RAI at the age of 50, an estimated lifetime excess of 18 to 31 solid cancer deaths would occur (including 4 to 6 breast cancers), most occurring more than 20 years after treatment with radioactive iodine. Afterward, she was allowed to go home but had to steer clear of other people–including her husband—for 48 hours to … However, in that study, there were high rates of relapse in those treated with an ATD (42% in the 20–34 age group and 34% in the 35–55 group) and more frequent eye problems in those treated with RAI. If these findings are confirmed in other studies in other countries, it would suggest that radioactive iodine therapy may be less desirable in the long term as compared to antithyroid drugs or surgery, Graves’ Disease: https://www.thyroid.org/graves-disease/, Hyperthyroidism (Overactive): https://www.thyroid.org/hyperthyroidism/, Radioactive Iodine: https://www.thyroid.org/radioactive-iodine/, Thyroid Surgery: https://www.thyroid.org/thyroid-surgery/. So after 8 days half of the radiation contained in the original dose will have decayed away (been released), and after another 8 days the residual will be half again. There are three main conventional treatment pathways for Graves disease: anti-thyroid drugs (ATDs), surgical removal of the thyroid (Thyroidectomy), and the destruction of the thyroid via radioactive iodine treatment … (also known as Graves’ disease, thyrotoxicosis and overactive thyroid) develops when your thyroid gland produces too much thyroxine, making your body clock run too fast. Graves’ disease is a common cause of hyperthyroidism and may be associated with a negative impact on patients’ quality of life (QoL) (1,2). Patients in surgery group were generally younger (average age 35 years, compared to 43 years for the antithyroid drug group and 54 years for the radioactive iodine therapy group). A publication of the American Thyroid Association, Summaries for the Public from recent articles in Clinical Thyroidology, Table of Contents | PDF File for Saving and Printing. Tay WL(1), Lee LMY(1), Tong AKT(2), Chng CL(1). Patients who were treated with RAI were generally older and more likely to have had comorbidities than those treated with ATD or surgery. Nsreen Ra Mohamadien Department of Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Assiut University Egypt. this time went for radioactive iodine treatment. Radioactive iodine Higher scores on SF-36 represent better health status. Is such a drastic treatment justifiable for Graves’ disease? Here are some ways to minimize radiation risks to other people (and pets) after you have had RAI treatment: 1. Radioactive Iodine (RAI), I 131 is one of the treatments for Graves’ disease and thyroid cancer. Abraham-Nordling M, Torring O, Hamberger B, et al. Iodine is normally concentrated by the thyroid gland and is used to make Moreover July 1, 2019. Graves’ disease is a common cause of an overactive thyroid gland (hyperthyroidism). Quality of Life Is Worse at 6-10 Years after Radioactive Iodine Treatment of Graves’ Disease as Compared with Antithyroid Drugs or Surgery Sun Y. Lee Section of Endocrinology, Diabetes, and Nutrition; Department of Medicine, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts, U.S.A. However, in the initial weeks of RAI treatment for Graves’ disease, blood thyroid levels actually rise, instead of declining. i had partial thyroidectomy after thyroid toxycosis 2003. got hyperthyroid again. 2. Studies have shown that having Graves’ disease may have negative impact on patient’s quality of life. Ozaki O(1), Ito K, Mimura T, Sugino K, Kitamura Y, Iwabuchi H, Kawano M. Author information: (1)Surgery Branch, … Strengths of the current study include a large sample size and long-term follow-up (mean, 8 years) after the initial diagnosis of Graves’ disease. Regardless of treatment method, patients with Graves’ disease had worse QoL measures at 6 to 10 years after diagnosis than the general population. It's the rare Graves bird that goes into remission without going hypo. Further studies to ascertain this observation would be needed, given the potentially important impact of choosing treatment options for patients with Graves’ disease in routine clinical practice. In 2000, I underwent radioactive iodine ablation (RAI) for Grave’s disease. WHAT ARE THE IMPLICATIONS OF THIS STUDY? This means avoiding public transportation, hotels, carpools, and in some cases, your workplace. still hyper but picked up 20+kg without changing diet. Abstract. I had radioactive iodine therapy for my Graves Disease two weeks ago. Robyn’s experience with RAI, Graves and a life forever impacted. Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves’ disease compared with treatment with antithyroid drugs or surgery. Previous studies have reported similar general-health QoL with the three treatment methods, but were limited to shorter-term follow up (3,4). In a change from current practice, the new guidelines of the National Institute for Health and Care Excellence (NICE) recommends that radioiodine should now be first line therapy for Graves’ disease. Radioactive iodine treatment (RAI) is usually the choice after an unsuccessful course of anti-thyroid medication. We report a case of GD with the longest time-to-relapse so far published, i.e. A report of 174 patients with Graves’ disease stratified by age and randomly assigned to ATD, surgery, or RAI treatment in Sweden had shown no significant differences in QoL at the 3-year follow-up (3). [5] Some who underwent RAI treatment suffer from some degree of damage to the stomach, salivary,[6] lacrimal (tear) glands[7] and other organs, because those organs also collect iodine. Thyroid 29:322–331. It not only precaution is when a person with the Jetta TDI are the vet for her four months to a young child the effects of papaya daily to overcome and have strange vague feelings that some people as the cause of cystic fibrosis. Graves’ disease is usually treated with antithyroid drugs, radioactive iodine … I am not here … Another long-term study of patients at 14 to 21 years after initial enrollment also did not show significant differences in QoL scores (4). It can be accompanied by extrathyroidal complications such as ophthalmopathy, dermopathy, and acropachy. Effectiveness of radioactive iodine (131I) in the treatment of Graves' disease: single center experience in Assiut University hospital. What is radioactive iodine treatment? It is a very effective treatment for thyroid cancer but what about Graves’ disease. I recieved the pills on a Thursday and was back to work the following Monday. It is a very effective treatment for thyroid cancer but what about Graves’ disease. There were 347 patients (36%) in the ATD group, 395 (41%) in the RAI group, and 233 (24%) in the surgery group. For a few days after radioactive iodine treatment, you will be slightly radioactive. Robyn’s experience with RAI, Graves and a life forever impacted. The diagnosis of Graves' disease may include: 1. In 2000, I underwent radioactive iodine ablation (RAI) for Grave’s disease. Radioactive Iodine Testing Depending on the dose, radioactive iodine can kill a portion, or all, of your thyroid. Among the three treatment groups, patients who received radioactive iodine treatment had worse thyroid-specific quality of life scores than patients treated with antithyroid drugs or surgery. 32 years after therapy with RAI. Usual treatment options include antithyroid drugs (ATDs), radioiodine (RAI), or surgery. Is such a drastic treatment justifiable for Graves’ disease? It's simple enough: 1. Median ages were significantly different for the treatment groups: 43 years (range, 33–55) for the ATD group, 54 years (range, 45–63) for the RAI group, and 35 years (range, 29–46) for the surgery group. If the address matches an existing account you will receive an email with instructions to reset your password. I was diagnosed with graves' disease a few months ago and stupidly enough I went through the Radioactive iodne (10 meq) process instead of the antithyroid meds. It is caused by antibodies that attack the thyroid and turn it on. Participants were divided in three groups: (i) patients treated with ATDs only, (ii) patients treated with RAI (with or without previous treatment with ATD), but not surgery, and (iii) patients treated with subtotal or total thyroidectomy (with or without previous treatment with ATD or RAI). Among the three treatment groups, patients who received radioactive iodine treatment had worse Treatment includes antithyroid drugs or medications, radiation therapy with radioactive iodine … The half-life of I131, used in radio-iodine treatment, is 8 days. After her original diagnosis of Graves’ disease, Williams decided on a single dose of radioactive iodine taken orally to destroy the misbehaving thyroid cells. Because Graves' disease increases your metabolism, your doctor will check your pulse and blood pressure and look for signs of tremor. QoL was assessed using the validated Swedish versions of the Thyroid-Related Patient-Reported Outcome Questionnaire (ThyPRO; n = 975) and the general 36-Item Short Form Health Status Survey (SF-36; n = 964) questionnaires completed by participants; scores from ThyPRO were compared with scores from a general population sample (n = 712). After 18 months of antithyroid therapy, similar monitoring is indicated to detect relapse or changes in thyroid function. I pushed my doctors to do it because I was allergic to the anti-thyroid medications (they shut down my white cells) and I really wanted a normalized thyroid so I could get pregnant and not have to deal with the Grave’s disease anymore. THE FULL ARTICLE TITLE: After her original diagnosis of Graves’ disease, Williams decided on a single dose of radioactive iodine taken orally to destroy the misbehaving thyroid cells. PMID: 30667296. Find out what happens after having radioactive iodine treatment. Additionally, another randomized study of 308 patients showed no difference in general QoL measures, as assessed by SF-36, after ATD or RAI treatment at 4-year follow-up (6). Radioactive Iodine treatment for Graves’ disease – what you should know. 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